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These success, along with a former report showing that a little-molecule ACKR3 agonist CCX771 displays anxiolytic-like behavior in mice,two help the idea of concentrating on ACKR3 as a singular approach to modulate the opioid procedure, which could open up new therapeutic avenues for opioid-linked Conditions.Tabernaemontana divaricata Conolidine ca